245例高脂血症口服非诺贝特的近期疗效观察,发现其具有明显的降血清胆固醇和甘油三酯的作用,有效率分别为81.4％及94.5％;平均下降率为22.6％及56.5％(p<0.001),在服药一个月时,即有明显下降。对高密度脂蛋白-胆固醇的提高亦有较好效果(78.7％),平均升高率29.2％(p<0.001)。副反应轻微,偶见血清谷丙转氨酶或尿素氮暂时性增高,停药后即恢复正常。本品远期疗效有待进一步观察。 245 cases of hyperlipidemia oral fenofibrate observed the short-term efficacy and found that it has significant serum cholesterol and triglyceride, the effective rates were 81.4% and 94.5%; the average rate of decline was 22.6% and 56.5% (p <0.001), a month when taking, that is, a significant decline. High-density lipoprotein cholesterol also improved (78.7%) with an average increase of 29.2% (p <0.001). Minor side effects, and occasionally serum alanine aminotransferase or urea nitrogen temporarily increased, stop returning to normal. The long-term efficacy of this product needs further observation.