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一般认为,克山病是以侵犯心肌为主的全身性疾病,但关于共病原及发病机制,现在尚无肯定的结论。有人依照心肌病理变化的特点进行分析,认为克山病患者心肌的病变可能是由冠状循环障碍所引起。根据病理切片的观察,克山病患者冠状循环的小血管每呈胶元膨化,管壁增厚,血浆蛋白浸润和分层变化等,而此外横纹肌、神经系统以及内脏器官中的小血管亦有类似的变化。虽然不能确定上述血管的变化是原发的或次发的,但是这对于疾病的发展过程
It is generally believed that Keshan disease is a systemic disease that mainly affects the myocardium, but there is no definite conclusion about the co-pathogens and pathogenesis. Some people in accordance with the characteristics of myocardial pathological changes were analyzed, that Keshan disease in patients with myocardial lesions may be caused by coronary circulatory disorders. According to the observation of pathological section, the small coronary vessels in Keshan disease showed bulging, wall thickening, plasma protein infiltration and delamination in every coronary circulation, and in addition, there were small vessels in striated muscle, nervous system and internal organs Similar changes. Although it is not certain that the above changes in blood vessels are primary or secondary, this is important for the development of the disease