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目的探讨胸腺肽注射液在食管癌术后化疗中的药物过敏反应。方法回顾分析在应用胸腺肽注射液的过程中出现过敏反应的5例患者,总结过敏反应发生的时间及其临床表现、治疗措施和治疗结果。结果胸腺肽注射液在用药过程中过敏反应比较快,比较剧烈,主要是对呼吸和血压的影响,由于及时采取抢救处理,过敏症状迅速缓解,均未引起严重的不良后果。结论胸腺肽作为免疫抑制剂,在临床上广泛应用,发生过敏反应的概率并不大,但是一旦发生,其来势较凶。如果没有临床经验,未得到重视,容易误诊误治,有可能引起严重不良后果。
Objective To investigate the drug allergic reaction of thymosin injection in postoperative chemotherapy of esophageal cancer. Methods A retrospective analysis of thymosin injection in the process of allergic reactions occurred in 5 patients, summarizes the occurrence of allergic reaction time and clinical manifestations, treatment measures and treatment results. Results Thymopeptide injection in the course of medication allergic reactions faster, more intense, mainly on the respiratory and blood pressure, due to timely rescue treatment, the rapid relief of allergy symptoms, did not cause serious adverse consequences. Conclusion As an immunosuppressive agent, thymosin is widely used clinically. The incidence of anaphylactic reaction is not large, but in the event of its occurrence, its tendency is fiercer. If there is no clinical experience, not paid attention, easy misdiagnosis, may cause serious adverse consequences.