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近来,脉冲多普勒实时超声已成为估价内脏血流的一种可靠的非侵入性方法。本文研究目的在于评价多普勒超声对正常人和肝硬化者在生理和药物刺激下门脉血流的测定效果。材料和方法:对照组12例为健康志愿者。19例肝硬化和1例肝静脉闭塞者为病人组(均有严重的门脉高压症)。试验组20例患者被随机分为2组:第1组10例随机服用安慰剂(水)或标准餐(均330ml)后10、20、30、60分钟测定。第2组10例随机服用安慰剂(水)或消心痛与5mg后5、10、15分钟测定。对所有受试者均采用脉冲多普勒实时超声测定其门脉管径、血流速率及血流量。统计分析结果以p<0.05作为有意义。结果:组1:在标准餐后门脉血流量明显增加(P<0.02),其峰值于餐后30分钟出现,同时血流速率也增
Recently, pulsed-Doppler real-time ultrasound has become a reliable, noninvasive method of assessing visceral blood flow. The purpose of this study is to evaluate the effect of Doppler ultrasound on portal vein blood flow in both normal and cirrhotic patients under physiologic and pharmacological stimuli. Materials and Methods: Control group of 12 healthy volunteers. Nineteen patients with cirrhosis and one with hepatic vein occlusion were patients (all with severe portal hypertension). Twenty patients in the experimental group were randomly divided into 2 groups: Group 1, 10 patients were randomized to receive placebo (water) or standard meal (330 ml each) at 10, 20, 30, and 60 minutes. The second group of 10 patients randomized to placebo (water) or ambroxol and 5mg after 5,10,15 minutes measured. All subjects were measured by pulse Doppler real-time ultrasound portal diameter, blood flow rate and blood flow. Statistical analysis results with p <0.05 as meaningful. RESULTS: Group 1: The portal blood flow increased significantly after the standard meal (P <0.02), with a peak at 30 minutes postprandial and at the same time the rate of blood flow increased