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目的探讨小儿肺炎支原体(MP)感染并中枢神经系统(CNS)受累的临床特点。方法对20例MP感染CNS受累患儿的临床表现、实验室检查、治疗转归情况进行回顾性分析。结果 MP感染CNS受累多见于学龄期儿童,临床表现为发热、头痛、呕吐、抽搐、嗜睡、精神萎靡、意识丧失,所有病例的血清抗P-lgM阳性,2例脑脊液抗P-lgM阳性,17例病愈出院,2例好转出院,1例转院治疗。结论中枢神经系统损害患儿如果临床上不能用病毒或细菌解释时要考虑到MP感染的可能,及时做血清和(或)脑脊液抗P-lgM检查,以便早期诊断及治疗。
Objective To investigate the clinical features of children with Mycoplasma pneumoniae (MP) infection and central nervous system (CNS) involvement. Methods The clinical manifestations, laboratory tests and treatment outcome of 20 children with MP-infected CNS were retrospectively analyzed. Results MP infection CNS involvement more common in school-aged children, clinical manifestations of fever, headache, vomiting, convulsions, drowsiness, apathetic, loss of consciousness, all cases of serum anti-P-lgM positive, 2 cerebrospinal fluid anti-P-lgM positive Two cases were discharged, one case was transferred to hospital. Conclusion Children with central nervous system damage should consider the possibility of MP infection if they can not be explained by viruses or bacteria clinically. Anti-P-lgM examination of serum and / or cerebrospinal fluid should be performed in time for early diagnosis and treatment.