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近年来自体骨髓移植治疗急性白血病受到人们广泛的重视,并获得一定的疗效。在自体骨髓移植中,大剂量化疗和全身照射后骨髓造血重建所需要的造血干细胞不仅可以从骨髓,而且还可以从外周血获得。由于从外周血分离造血干细胞比较方便,可重复进行,并且在缓解的早期其所含的残存的白血病细胞有可能比较少,因而具有一定的优点。为了避免在骨髓保存和“净化”过程中因意外造成不良后果,我们用 Haemonetics V_(50)从1例巩固化疗后的急性粒细胞白血病患者的外周血采集到较大量的造血干细胞,保存备用。
In recent years, autologous bone marrow transplantation for acute leukemia has received widespread attention and achieved a certain effect. In autologous bone marrow transplantation, hematopoietic stem cells required for bone marrow hematopoietic reconstitution following high-dose chemotherapy and systemic irradiation can be obtained not only from the bone marrow but also from peripheral blood. Since the separation of hematopoietic stem cells from peripheral blood is more convenient and repeatable, and may contain fewer residual leukemia cells in the early stage of remission, it has certain advantages. In order to avoid unintentional adverse consequences during bone marrow preservation and “decontamination”, Haemonetics V 50 was used to collect larger quantities of hematopoietic stem cells from the peripheral blood of 1 patient with consolidation-chemotherapy acute myeloid leukemia for later storage.