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目的了解江苏省东海县环境碘含量、居民碘盐食用情况及特殊人群碘营养状况,查找防制过程中存在的问题和薄弱环节,为调整干预措施提供依据。方法采取随机抽样的方法,对该县49个水厂饮用水进行碘含量检测、对批发层次的6个批次盐碘含量、300户居民食用盐碘含量进行检测,对1 044名学龄儿童和260名育龄妇女尿样进行碘含量检测,对19 865例新生儿全血进行促甲状腺激素(TSH)检测。结果水碘中位数为8.4μg/L,<10μg/L的占61.22%;批发层次盐碘批合格率为100%,盐碘范围为18.3~29.2 mg/kg;居民户碘盐覆盖率为99.67%,碘盐合格率为97.99%,合格碘盐食用率为98.00%。儿童尿碘范围为12.7~986.1μg/L,尿碘中位数为172.6μg/L,<100μg/L的占14.37%,>300μg/L的占3.45%;孕妇尿碘范围为12.6~1 075.9μg/L,中位数为171.61μg/L,<150μg/L的占37.89%,>500μg/L的占3.1%;哺乳期妇女尿碘范围为5.6~514.2μg/L,中位数为146.0μg/L,<100μg/L的占27.3%,>300μg/L的占7.1%;新生儿全血TSH>5 m U/L的比率为0.96‰。结论东海县已达到控制碘缺乏危害标准,但部分地区仍存在非碘盐和不合格碘盐,少部分学龄儿童和育龄妇女仍存在缺碘和碘摄入量过高的问题。
Objective To understand the iodine content in environment, the consumption of iodized salt and the iodine nutrition status of residents in Donghai County, Jiangsu Province, find out the problems and weak links in the prevention and control process, and provide the basis for adjusting the intervention measures. Methods The iodine content of 49 batches of drinking water in this county was tested by random sampling method. Salt iodine content of 6 batches of salt and iodine content of 300 inhabitants of the wholesale level were tested. Urinary samples from 260 women of childbearing age were tested for iodine content, and thyrotropin (TSH) was detected in 19 865 neonates with whole blood. Results The median iodine concentration in water was 8.4 μg / L, accounting for 61.22% in the range of <10 μg / L. The salt iodine yield in the wholesale level was 100% and the range of salt iodine was 18.3-29.2 mg / kg. 99.67%, iodized salt pass rate of 97.99%, qualified iodized salt consumption rate of 98.00%. Urinary iodine ranged from 12.7 to 986.1 μg / L in children, and median urinary iodine was 172.6 μg / L, with <100 μg / L accounting for 14.37% and> 300 μg / L accounting for 3.45%; urinary iodine in pregnant women ranging from 12.6 to 1075.9 L, the median was 171.61μg / L, <150μg / L accounted for 37.89%,> 500μg / L accounted for 3.1%; lactation women with urinary iodine range of 5.6 ~ 514.2μg / L, the median was 146.0 μg / L, <100μg / L accounted for 27.3%,> 300μg / L accounted for 7.1%; neonatal whole blood TSH> 5mU / L ratio was 0.96 ‰. Conclusion Donghai County has reached the standard of controlling iodine deficiency, but non-iodized salt and unqualified iodized salt still exist in some areas. Few iodine deficiency and excessive iodine intake still exist in a small number of school-age children and women of child-bearing age.