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目的观察盐酸纳美芬联合亚低温治疗重症病毒性脑炎的临床疗效。方法将62例患儿分为观察组和对照组,对照组给予常规治疗,观察组在常规治疗基础上给予盐酸纳美芬联合亚低温治疗,观察两组患儿的治疗效果。结果观察组患儿发热、惊厥、昏迷持续时间及在PICU住院时间较对照组缩短,其有效率高,致残率低,两组比较差异有统计学意义。结论盐酸纳美芬联合亚低温治疗重症病毒性脑炎疗效显著。
Objective To observe the clinical efficacy of nalmefene hydrochloride combined with mild hypothermia in the treatment of severe viral encephalitis. Methods Sixty-two children were divided into observation group and control group. The control group was given routine treatment. The observation group was treated with nalmefene hydrochloride combined with mild hypothermia on the basis of routine treatment. The therapeutic effect was observed in both groups. Results The fever, convulsion, duration of coma and the length of stay in PICU patients in observation group were shorter than those in control group. The effective rate and the rate of disability in observation group were significantly lower than the control group. There was significant difference between the two groups. Conclusion Nalmefene hydrochloride combined with mild hypothermia is effective in treating severe viral encephalitis.