自70年代后期观察到牛、猪的卵泡液中存在着抑制素样活性物质以来,许多文献已对其生理作用、分离纯化以及分泌调控进行了初步的阐述,甚至深入研究了其组成结构的部分氨基酸序列,现有资料表明:抑制素是由卵泡颗粒细胞产生、对垂体细胞FSH分泌具有特异性抑制作用的非类固醇物质。本文就其对FSH分泌、对卵泡发育和排卵的抑制作用、以及卵泡抑制素的分泌调控加以概述。 Since the late 1970s, it has been observed that there are statin-like active substances in the follicular fluid of cattle and pigs. Many literatures have initially described their physiological roles, isolation and purification, and regulation of secretion, and have even studied in depth the part of their constitutional structure Amino acid sequences, available data show that: inhibin is produced by follicular granulosa cells, pituitary FSH secretion has a specific inhibitory effect of non-steroidal substances. This article summarizes its inhibitory effects on FSH secretion, follicular development and ovulation, and the regulation of follicle-stimulating hormone secretion.