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羟基喜树碱（HCPT）是从珙垌科植物喜树中提取得到的微量生物碱。近年来由于发现了它可选择性地抑制拓扑异构酶（TOPO－I），干扰DNA的复制而日益受到重视[1]。我科自1996年1月开始，至1997年9月，应用湖北黄石飞云制药有限公司生产的HCPT注射液。单药治疗多种晚期耐药恶性肿瘤
Hydroxycamptothecin (HCPT) is a trace alkaloid extracted from Camptotheca acuminata. In recent years, due to its discovery that it can selectively inhibit topoisomerase (TOPO-I) and interfere with the replication of DNA, it has been increasingly valued [1]. Our department started from January 1996 to September 1997 and applied HCPT injection produced by Hubei Huangshi Feiyun Pharmaceutical Co., Ltd. Single drug treatment for multiple late drug resistant malignancies