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自Todd等于1978年首先提出“中毒性休克综合征”(简称TSS)后,Schrock又首先报道了TSS与病妇使用阴道栓所引起的葡萄球菌感染有关。最近Jacobson报道了鼻腔是葡萄球菌检出率最高的部位之一,鼻脏手术后常易发生本病,本文将TSS病原与病因的有关文献综述如下。 Todd等首先提出TSS的病原菌是能产生中毒性休克毒素(toxic shocke toxin,TST)的金黄色葡萄球菌(简称金葡菌),且主要是噬菌体Ⅰ群的金葡菌(60％),其中以29型噬菌体为常见,其余也有Ⅱ、Ⅲ群的。多数TSS金葡菌株耐青霉素、砷酸盐及镉。这类金葡菌的溶血性较差。TSS与金
Since Todd first proposed “toxic shock syndrome” (TSS) in 1978, Schrock first reported on the involvement of TSS in staphylococcal infections caused by vaginal suppositories in women. Recently, Jacobson reported that the nasal cavity is one of the sites with the highest detection rate of Staphylococcus aureus. This disease often occurs after nasal surgery. The relevant literature on the pathogens and etiology of TSS is summarized as follows. Todd et al. First proposed that the pathogen of TSS is Staphylococcus aureus (Staphylococcus aureus) capable of producing toxic shock toxin (TST), and mainly Staphylococcus aureus (60%) of bacteriophage group I, Type 29 phage are common, the rest also have Ⅱ, Ⅲ group. Most strains of TSS Staphylococcus aureus resistant to penicillin, arsenate and cadmium. Such Staphylococcus aureus is less hemolytic. TSS and gold