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目的对比分析多种不同梅毒检验方法测定梅毒螺旋体的准确率。方法选取我中心2015年3月至2016年3月收治的梅毒患者96例作为观察组,再选取同期健康无梅毒人员96例作为对照组,所有患者均通过梅毒螺旋体明胶颗粒凝集(TPPa)、梅毒甲胺红不加热血清反应素(TRu ST)以及梅毒酶联免疫吸附法(e Li Sa)等试验方法进行检测,并比较所得结果。结果(1)TPPa、TRu ST、e Li Sa的阳性检出率分别为95.8%、88.5%、94.5%;(2)TPPa、TRu ST、e Li Sa的敏感性分别为95.8%、88.5%、94.8%,特异性分别为97.9%、94.8%、98.9%。结论 TPPa、TRu ST、e Li Sa三种梅毒检测方法相结合使用,更能有效减少误诊、漏诊现象,提高检出率,值得临床推广应用。
Objective To compare and analyze the accuracy of different syphilis test methods for the determination of Treponema pallidum. Methods Ninety-six patients with syphilis who were admitted to our center from March 2015 to March 2016 were selected as the observation group. 96 healthy people without syphilis were enrolled in the study. All the patients were infected with syphilis particles (TPPa), syphilis Methionine unheated serotonin (TRu ST) and syphilis enzyme-linked immunosorbent assay (e Li Sa) and other test methods were tested, and the results obtained were compared. Results (1) The positive detection rates of TPPa, TRu ST and e Li Sa were 95.8%, 88.5% and 94.5% respectively. (2) The sensitivity of TPPa, TRu ST and e Li Sa were 95.8% and 88.5% 94.8%, specificity was 97.9%, 94.8%, 98.9% respectively. Conclusions The combined use of TPPa, TRu ST and e Li Sa syphilis detection methods can effectively reduce the misdiagnosis and missed diagnosis and increase the detection rate, which is worthy of clinical application.