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目的:分析干预前后余杭区第一人民医院普外科围术期患者抗生素使用情况,为临床加强合理用药管理提供参考。方法:选取余杭区第一人民医院2013年2月~2014年2月收治的普外科围术期患者120例作为干预前组,2015年2月~2016年2月收治的普外科围术期患者120例作为干预后组,收集两组患者的住院时间、药物费用、用药合理性、用药时机合理性数据并进行比较分析,得出结论。结果:干预后组患者的住院时间、药物费用均低于干预前组(P<0.05);干预后组的用药合理性为91.67%,干预前组的用药合理性为82.5%,干预后组显著高于干预前组(P<0.05);干预后组的用药时机合理性为90.83%,干预前组的用药时机合理性为81.67%,干预后组显著高于干预前组(P<0.05)。结论:应用合理有效的干预措施对普外科围术期患者进行干预,可以有效减少患者住院时间和药物费用,改善患者的抗生素使用情况,提高抗生素使用合理性。
OBJECTIVE: To analyze the antibiotic use in perioperative period of General Surgery in First People’s Hospital of Yuhang District before and after intervention, and to provide reference for clinical management of rational drug administration. Methods: A total of 120 cases of perioperative patients admitted to the First People’s Hospital of Yuhang District from February 2013 to February 2014 were enrolled as pre-intervention group, general surgery perioperative patients from February 2015 to February 2016 120 cases were taken as the intervention group. The hospitalization time, drug cost, medication rationality and rationality of medication timing were collected and compared between the two groups. Conclusions were drawn. Results: After the intervention, the hospitalization time and the cost of medicine in the intervention group were all lower than those in the intervention group (P <0.05). The rationality of the medication in the intervention group was 91.67%, and the rationality of medication in the intervention group was 82.5% (P <0.05). After the intervention, the rationality of the medication was 90.83% in the intervention group, 81.67% in the intervention group, and significantly higher in the intervention group than in the pre-intervention group (P <0.05). Conclusion: The intervention of reasonable and effective interventions for general surgery perioperative patients can effectively reduce the hospitalization time and medication costs, improve the patient’s antibiotic use and improve the rational use of antibiotics.