采用pH 3.2,360 mmol/L酒石酸缓冲体系,毛细管区带电泳能成功地将烟草生物碱基线分离.与磷酸缓冲液相比,该方法提高了分离度和检测灵敏度.米喔斯明的分离度和检出限分别为1.6和2 ng/mL.此外,还研究和采用了卷烟样品中痕量生物碱的毛细管电泳阳离子选择性耗尽在柱富集方法. Tobacco alkaloid baselines were successfully separated by capillary zone electrophoresis using a tartaric acid buffer system at pH 3.2 and 360 mmol / L, which improved the resolution and detection sensitivity compared with phosphate buffer solution. Degrees and detection limits were 1.6 and 2 ng / mL respectively.In addition, column-based enrichment was also performed on the selective depletion of Cationic Capillary Electrophoresis using trace amounts of alkaloids in cigarette samples.