论文部分内容阅读
目的:分析泌尿生殖道支原体阳性患者及其抗菌药物的耐药性,为临床合理使用抗菌药物提供参考。方法:从2014年3月—2016年7月间收治的妇科、皮肤科和泌尿外科589例患者所采集的标本,采用标本培养、鉴定、药敏一体化试剂盒(珠海迪尔试剂股份有限公司生产提供)分析其药敏结果。结果:解脲支原体(UU)对氧氟沙星和环丙沙星的耐药率分别为41.31%和80.24%;除红霉素和司帕沙星外,其他抗菌药物的敏感性较为适中,可以用于抗菌药物的经验性治疗;人型支原体(MH)+解脲支原体(UU)及人型支原体(MH)对美满霉素、强力霉素和四环素的敏感性较高,其他抗菌药物的耐药率为70%~90%。结论:对疑为非淋菌性泌尿生殖道炎症患者,应采用支原体培养和药敏试验法,根据结果合理选择抗菌药物治疗,以减少耐药菌株的发生,提高治疗效果;对无条件做支原体药敏试验的医疗机构,应采用强力霉素、交沙霉素和美满霉素作为治疗支原体感染的首选药。
OBJECTIVE: To analyze the drug resistance of patients with genitourinary tract mycoplasma positive and its antibacterials, and provide a reference for the rational use of antibacterials in clinic. Methods: The samples collected from 589 patients in gynecology, dermatology and urology admitted from March 2014 to July 2016 were collected by using specimen culture, identification and drug sensitivity integration kit (Zhuhai Deer Reagent Co., Ltd. Production provided) to analyze its susceptibility results. Results: The susceptibilities of UU to ofloxacin and ciprofloxacin were 41.31% and 80.24%, respectively. The sensitivity of other antibiotics was moderate except erythromycin and sparfloxacin, Can be used for the empirical treatment of antimicrobial agents; Mycoplasma hominis (UU) and Mycoplasma hominis (MH) are more sensitive to minocycline, doxycycline and tetracycline; other antibacterials Resistance rate of 70% to 90%. Conclusions: Mycoplasma suspicious genitourinary tract inflammation patients should adopt mycoplasma culture and drug susceptibility test method, according to the results of a reasonable choice of antimicrobial agents to reduce the incidence of drug-resistant strains and improve the therapeutic effect of unconditional do Mycoplasma sensitivity Test medical institutions, should be used doxycycline, josamycin and minocycline as the drug of choice for the treatment of mycoplasma infection.