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目的:本研究探讨牙周非手术治疗对慢性牙周炎患者牙周状况及血管内皮功能的影响.方法:选取于2016年3月一2017年10月在本院收治口腔科患者共31例,均进行牙周非手术治疗,监测治疗前后PD、PLI和BI,血流介导的肱动脉扩张指数,硝酸甘油介导的肱动脉扩张指数.结果:与治疗前比较,在牙周非手术治疗3个月后,患者的牙周状况明显改善,PD、PLI和BI均显著性下降(P＜0.01),血流介导的肱动脉扩张指数显著改善(P＜0.01),硝酸甘油介导的肱动脉扩张指数无明显变化(P＞0.05).结论:慢性牙周炎患者进行牙周非手术治疗后,可以明显改善牙周状况,以及改善血管内皮细胞功能,降低血栓及动脉粥样硬化风险.","Objective In this study, the effects of periodontal nonsurgical treatment on the periodontal status and vascular endothelial function of patients with chronic periodontitis were investigated. Methods A total of 31 patients in Department of Stomatology were selected from March 2016 to October 2017. All patients were treated with nonoperative periodontal treatment PD, PLI and BI、the blood flow mediated brachial artery dilatation index and nitroglycerin mediated brachial artery dilatation index were monitored before and after treatment Results Compared with before treatment, after non-surgical periodontal treatment after 3 months, patients with periodontal status improved significantly, PD, PLI and BI were significantly decreased (P＜0.01), brachial artery flow mediated dilation index improved significantly (P＜0.01), brachial artery dilation index nitroglycerin mediated no significant changes (P＞ 0.05). Conclusion Nonperiodontal treatment of periodontitis patients can significantly improve periodontal condition, improve vascular endothelial cell function and reduce thrombosis and atherosclerosis risk.