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报道榄香烯乳加联合化疗治疗急性非淋巴细胞白血病的疗效。方法:将43例急性非淋巴细胞白血病患者随机分为治疗组,用榄香烯乳200~400mg加生理盐水或5%葡萄糖500ml,静脉滴注,持续12~15天,同时用HA方案:三尖杉酯碱4~6mg/d1-7,阿糖胞苷100-200mg/d1~7;对照组:单用HA方案,用量用法同治疗组。结果:治疗组CR率80%,对照组CR率60.9%;治疗组有效率95%,对照组有效率73.9%。结论:榄香烯乳对急性非淋巴细胞白血病有肯定的疗效,此药不良反应轻,无骨髓抑制,在化疗后的骨髓抑制期仍能继续使用榄香烯乳治疗,故榄香烯乳可成为急性非淋巴细胞白血病的有效药物之一。
Elemenelin plus chemotherapy was used to treat acute nonlymphocytic leukemia. METHODS: Forty-three patients with acute non-lymphocytic leukemia were randomly divided into treatment groups, with elemene milk 200-400 mg plus normal saline or 5% glucose 500 ml, intravenous drip for 12 to 15 days while using HA regimen: III Telomere base 4 ~ 6mg/d1-7, cytarabine 100-200mg/d1 ~ 7; control group: single HA program, dosage usage with the treatment group. Results: The CR rate was 80% in the treatment group and 60.9% in the control group. The treatment group had an effective rate of 95% and the control group had an efficiency of 73.9%. Conclusion: Elemene milk has a positive effect on acute non-lymphocytic leukemia. The adverse drug reaction is mild and there is no bone marrow suppression. Elemene emulsion can still be used in the bone marrow suppression period after chemotherapy. Become one of the effective drugs for acute non-lymphocytic leukemia.