一例与服用活麻疹疫苗有关的Reye症候群的病案,促使作者对类似资料的研究。本文总结了作者的一些发现。 Reye症候群的定义是(1)急性非炎症性脑病,其特征为脑脊液白细胞低于8/mm~3或者脑组织切片显示有脑水肿而无脑膜或血管周围炎症,(2)活检或尸检显示肝脏有脂肪性变证据,或者SGOT或SGPT高出正常3倍或血氨水平高出正常1.5倍,以及(3)无其他原因可以解释神经系统或肝脏的异常。作者调查了Reye症候群404例;其中23例曾于病前一月内接受过“免疫”,内有14例在Reye症候群前驱症状开始前一月内接受过活病毒疫苗;另一例没有任何疫苗接种史,但却培养出了脊髓灰质炎病毒。本文分 A case of Reye syndrome associated with live measles vaccine prompted the authors to study similar information. This article summarizes some of the authors’ findings. Reye’s syndrome is defined as (1) acute noninflammatory encephalopathy characterized by cerebrospinal fluid leukocytes less than 8 / mm-3 or brain tissue sections showing cerebral edema without meningeal or perivascular inflammation, (2) biopsy or autopsy showing liver There is evidence of fatty degeneration, either SGOT or SGPT 3 times higher than normal or blood ammonia level 1.5 times higher than normal, and (3) Nervous system or liver abnormalities can be explained for no other reason. The authors investigated 404 Reye’s syndromes; of these, 23 had “immunization” within one month prior to disease and 14 had a live vaccine within one month prior to the onset of Reye’s syndrome; another did not have any history of vaccination , But poliovirus has been raised. This article points