目的观察前列地尔联合丹红注射液治疗急性脑梗死的临床效果。方法选取医院收治的急性脑梗死患者88例为研究对象,随机分为观察组和常规组,每组44例。全部患者均实施基础治疗,常规组在基础治疗上采用丹红注射液;观察组在常规组治疗基础上加用前列地尔治疗。观察2组患者临床治疗效果、日常活动能力改善情况、神经功能缺损评分及血清C反应蛋白变化情况。结果观察组总有效率为93.18%,高于常规组的72.72%(P<0.05);治疗后,观察组患者日常活动能力改善情况优于对照组(P<0.05);治疗后2组血清C反应白蛋及神经功能缺损评分均显著改善,且观察组患者改善程度优于常规组(P<0.05)。结论临床治疗急性脑梗死患者,予以前列地尔联合丹红注射液进行治疗,可改善患者血清C反应蛋白、神经功能缺损评分,提高临床疗效及生存质量,值得临床推广应用。 Objective To observe the clinical effect of alprostadil combined with Danhong injection in the treatment of acute cerebral infarction. Methods Eighty-eight patients with acute cerebral infarction admitted to hospital were selected as study subjects and randomly divided into observation group and conventional group, 44 cases in each group. All patients were treated with basic treatment, Danhong injection was used on the basis of the conventional treatment in the conventional group. The observation group was treated with alprostadil on the basis of the conventional treatment. The clinical effects, improvement of daily activities, neurological deficit score and changes of serum C-reactive protein in the two groups were observed. Results After treatment, the total effective rate of observation group was 93.18%, which was higher than 72.72% (P <0.05) of conventional group. After treatment, the improvement of daily activities ability of observation group was better than that of control group (P <0.05) Reactive white eggs and neurological deficit scores were significantly improved, and the observation group patients improved better than the conventional group (P <0.05). Conclusion The clinical treatment of patients with acute cerebral infarction, prostaglandin combined with Danhong injection for treatment, can improve patients with serum C-reactive protein, neurological deficit score, improve clinical efficacy and quality of life, worthy of clinical application.