活动性麻风和麻风逆向反应的临床症状都反映了机体对麻风杆菌抗原的细胞免疫反应。从临床角度来看,很难将这两者加以区别。组织病理学对这两者的差异也常难以下结论。细菌学检查也没有多大帮助,因为少菌型病人的皮肤涂片常常是阴性。虽然总的来说,终止治疗后逆向反应出现比复发早,但有时也会在终止治疗后一年或更长时间后发生。到目前为止,虽然报告联合化疗(MDT)后复发的时间资料不多,但从初步的资料来看,完成 MDT 后的前几年内,复 The clinical symptoms of active leprosy and leprosy reverse reactions all reflect the cellular immune response to the M. leprae antigen. From a clinical point of view, it is difficult to distinguish the two. Histopathological differences between the two are often difficult to draw conclusions. Bacteriological examination does not help much either, as skin smears in less-germ-type patients are often negative. Although in general the reverse response appears to be earlier than termination of treatment after termination of treatment, it can sometimes occur a year or more after termination of treatment. So far, although there is not much data on the timing of recurrence after combined chemotherapy (MDT), from the preliminary data, within the first few years after completion of MDT,