对牛布氏菌病化学治疗方案的设计必须考虑到牛种布氏菌是一种兼性细胞内寄生菌。这种细菌在网状内皮系统中能避开抗体、补体和抗生素的破坏而在吞噬细胞内存活。脂质体作为药物的载体正被广泛地研究着,存在于这些脂质体内的抗生素成分也已证实。脂质体特别能够把药物运送到吞噬细 The design of a chemotherapy regimen for bovine brucellosis must take into account that B. bovinus is a facultative intracellular parasite. This bacteria in the reticuloendothelial system can avoid the destruction of antibodies, complement and antibiotics in the phagocyte survival. Liposomes are being widely studied as carriers for drugs, and antibiotic components present in these liposomes have also been demonstrated. Liposomes are particularly capable of delivering drugs to phagocytes