论文部分内容阅读
目的:分析彩色多普勒超声(CDFI)在乳腺癌新辅助化疗(NAC)效果中的评估价值。方法:回顾性分析2018年1月至2019年4月内蒙古自治区肿瘤医院接受NAC后行手术治疗的乳腺癌患者100例，根据化疗效果将其分为有效组、无效组，对比两组NAC前后病灶大小、超声表现、病灶内血流分级、阻力指数(RI)与收缩期峰值速度(PSV)变化。结果:有效组NAC后肿块长度[(2.03±0.24)cm]、宽度[(1.69±0.24)cm]、厚度[(1.06±0.14)cm]、体积[(3.64±0.39)cmn 3]均小于NAC前[(3.40±0.36)cm、(2.35±0.26)cm、(1.78±0.19)cm、(14.24±1.53)cmn 3]及无效组NAC后[(3.31±0.34)cm、(2.36±0.27)cm、(1.76±0.19)cm、(14.19±1.42)cmn 3](n P<0.05)；有效组NAC后病灶形态规则、边界清晰、内部回声偏多、后方回声无异常的比例较NAC前差异有统计学意义(n P0.05)；有效组NAC后边界清晰、内部回声偏多的比例高于无效组(n P<0.05)；有效组NAC后病灶内血流分级低于无效组(n P<0.05)；有效组NAC后RI(0.54±0.06)低于无效组(0.65±0.08)(n P0.05)。n 结论:CDFI用于乳腺癌患者NAC效果评估中有较高价值，可对其病灶大小、血流改变等进行有效测量和判断，为临床评估疗效提供依据。“,”Objective:To analyze the value of color Doppler flow imaging (CDFI) in evaluating effects of neoadjuvant chemotherapy (NAC) for breast cancer.Methods:100 patients with breast cancer who underwent surgery after NAC in Cancer Hospital of Inner Mongolia Autonomous Region from January 2018 to April 2019 were selected for retrospective analysis. According to effects of chemotherapy, they were divided into effective group and ineffective group. The changes in lesion size, ultrasound findings, grade of blood flow in lesions, resistance index (RI) and peak systolic velocity (PSV) before and after NAC were compared between the two groups.Results:The length, width, thickness and volume of masses in effective group after NAC [(2.03±0.24)cm, (1.69±0.24)cm, (1.06±0.14)cm, (3.64±0.39)cmn 3] were smaller than those before NAC [(3.40±0.36)cm, (2.35± 0.26)cm, (1.78±0.19)cm, (14.24±1.53)cmn 3] and those in ineffective group after NAC [(3.31±0.34)cm, (2.36±0.27)cm, (1.76±0.19)cm, (14.19±1.42)cmn 3] (n P<0.05). After NAC, the the proportion of regular shape, clear boundary, more internal echo, and no abnormal posterior echo in effective group was statistically significant (n P0.05). The proportion of clear boundary and excessive internal echo in the effective group was higher than that in the ineffective group (n P<0.05); the blood flow grade of the effective group after NAC was lower than that of the ineffective group (n P<0.05) After NAC, the RI (0.54±0.06) in effective group was lower than that in ineffective group (0.65±0.08) (n P0.05).n Conclusions:The value of CDFI is high in evaluating NAC effect on patients with breast cancer. It can effectively measure and judge lesion size and blood flow changes, and provide basis for clinical curative effect evaluation.