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[目的]探讨经皮肝胆道内涵管置入治疗梗阻性黄疸的疗效及并发症。[方法]对48例梗阻性黄疸患者分为两组,28 例为内涵管组,行经皮肝穿胆道内涵管置入术;20例为对照组,用一般内科治疗(利胆、护肝等对症处理)。其中内涵管组28例随 访 35至 356天,观察近中期疗效和并发症。[结果]内涵管组:经皮肝胆道内涵管置入术技术成功率为 100%。置入后血清总胆红 素水平较置入前明显下降(P<0.05)。对照组:随时间的延长血清总胆红素水平较治疗前明显上升(P<0.001)。开通时间平均为 98天,半年开通率为53.57%。内涵管组:并发症发生率24.95%,主要为胰腺炎和逆行胆道感染等,对照组:井发症发生率30%(P <0.05)[结论]经皮肝胆道内涵管置入术疗效可靠、安全,可作为胆管阻塞介入治疗的另一种选择。
[Objective] To investigate the efficacy and complications of percutaneous transhepatic biliary endoprosthesis treatment for obstructive jaundice. [Methods] Forty-eight patients with obstructive jaundice were divided into two groups: 28 cases of intrinsic ducts, percutaneous transhepatic biliary endoprosthesis; 20 cases of control group, with general medical treatment (biliary, liver protection, etc.) Symptomatic treatment). The 28 patients in the intrinsic tube group visited 35 to 356 days, and observed the efficacy and complications in the near and medium term. [Results] Intrinsic tube group: Percutaneous transhepatic biliary endoprosthesis technique was successful in 100%. Serum total bilirubin levels after implantation were significantly lower than those before implantation (P<0.05). Control group: Serum total bilirubin levels increased significantly with time (P<0.001). The average opening time is 98 days, and the half-year opening rate is 53.57%. Intrinsic tube group: The incidence of complications was 24.95%, mainly pancreatitis and retrograde biliary tract infections, and the control group: Incidence of complications was 30% (P < 0.05) [Conclusion] Percutaneous transhepatic biliary tract intension management The curative effect is reliable and safe, and it can be used as another option for interventional treatment of bile duct obstruction.