近年来,抗青光眼显微手术和药物治疗已取得很大进展。但青光眼滤过性手术后2年内的失败率仍达15％～30％,其主要原因是手术区的瘢痕化。为减少滤过道的瘢痕形成,国内外许多学者研究应用抗瘢痕药物,其中最主要的是5-氟尿嘧啶(5-Fu)与丝裂霉素C(MMC),使手术成功率大为提高。但由于此两种药物的细胞毒性作用造成眼部的一些并发症,使其在临床 In recent years, anti-glaucoma microsurgery and medical treatment have made great progress. However, the failure rate within two years after glaucoma filtration surgery is still up to 15% to 30%, the main reason is the surgical area scarring. In order to reduce the scar formation of the filter tract, many scholars at home and abroad have studied the application of anti-scarring drugs, of which 5-fluorouracil (5-Fu) and mitomycin C (MMC) are the most important, which greatly improves the success rate of surgery. However, due to the cytotoxic effects of these two drugs cause some complications of the eye, make it in the clinic