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目的:探讨采用肠内营养乳剂(TPF)行肠内营养(EN)对急性脑卒中伴吞咽困难病人营养状态和免疫功能的改善作用。方法:将62例符合入选标准同期收治的急性脑脑卒中病人,随机分为治疗组和对照组,每组各31例。分别采用肠内营养乳剂和自制营养匀浆进行EN支持30 d。比较两组病人治疗前后的营养相关指标和免疫功能指标,记录并比较两组病人治疗前后不良反应的发生率。结果:两组病人的体重指数、肱三头肌皮皱厚度、上臂肌围等治疗后较治疗前均有不同程度下降,但治疗组病人与对照组比有显著性差异(P<0.05)。治疗组病人经治疗后血红蛋白、血清清蛋白、前清蛋白均较对照组升高,差异有显著性统计学意义(P<0.05),并且不良反应的发生率亦显著低于对照组(P<0.05)。结论:急性脑卒中病人应用肠内营养乳剂TPF行EEN支持,可明显改善机体的营养状态、降低并发症的发生率,且病人耐受良好。
Objective: To investigate the effect of enteral nutrition (TPF) enteral nutrition (EN) on nutritional status and immune function in acute stroke patients with dysphagia. Methods: Sixty-two acute cerebral apoplexy patients who met the inclusion criteria were randomly divided into treatment group and control group, with 31 cases in each group. Enteral nutrition emulsion and homemade nutrition homogenate were used to support EN for 30 days respectively. The nutritional indexes and immune function indexes of two groups before and after treatment were compared. The incidence of adverse reactions was recorded and compared between the two groups before and after treatment. Results: Body mass index, triceps skinfold thickness and upper arm muscle circumference decreased after treatment in both groups, but the difference between the two groups was significant (P <0.05). After treatment, the hemoglobin, serum albumin and prealbumin in the treatment group were significantly higher than those in the control group (P <0.05), and the incidence of adverse reactions was also significantly lower than that in the control group (P < 0.05). Conclusion: The application of enteral nutrition emulsion TPE to EEN in acute stroke patients can significantly improve the nutritional status of the body and reduce the incidence of complications, and the patients are well tolerated.