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目的:优化加味藿香正气滴丸提取工艺参数,提高有效成分提取率。方法:采用正交设计法对加味藿香正气滴丸进行提取工艺研究。结果:广藿香等5味药挥发油提取的最佳工艺为用10倍水浸泡0.5 h后加热蒸馏6 h;厚朴的最佳工艺为用8倍60%乙醇回流提取3次,每次1 h;半夏等7味药与提取挥发油后的药渣混匀进行提取,最佳工艺为加6倍水煎煮3次,每次煎煮1 h。结论:该优化工艺稳定、合理、可行,重复性好。
Objective: To optimize the extraction process parameters of Huoxiangzhengqi dropping pills and improve the extraction rate of active ingredients. Methods: The orthogonal design was used to study the extraction process of Modified Huoxiangzhengqi Dropping Pills. Results: The optimum extraction technology of volatile oil from 5 medicinal herbs such as patchouli was heated for 6 h by soaking in 10 times of water for 6 h. The optimum process of Magnolia officinalis was that it was refluxed 3 times with 8 times 60% h; pinellia and other 7 herbs and the extraction of volatile oil residue mixed extraction, the best technology for 6 times boiling water 3 times, each boiling 1 h. Conclusion: The optimization process is stable, reasonable, feasible and reproducible.