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目的评价两种方法静脉滴注丙种球蛋白(IVIG)治疗小儿川崎病(KD)的临床疗效。方法 64例KD患儿随机分为两组,A组为IVIG0.4 g/(kg.d),连用5 d;B组为IVIG1.0 g/(kg.d),连用2 d;比较两组患儿症状缓解情况和冠状动脉损害发生率及恢复情况。结果两组患儿治疗后比较,差异有统计学意义(P<0.05)。结论静脉注射丙种球蛋白1.0 g/(kg.d)连用2 d静脉注射,是一种更有效、简便的治疗方案。
Objective To evaluate the clinical efficacy of intravenous infusion of gamma globulin (IVIG) in children with Kawasaki disease (KD). Methods Sixty-four children with KD were randomly divided into two groups. Group A was IVIG 0.4 g / (kg · d) for 5 days, group B was IVIG 1.0 g / (kg · d) for 2 days, Group of children with symptoms and coronary lesions to reduce the incidence and recovery. Results After treatment, the differences between the two groups of children were statistically significant (P <0.05). Conclusion intravenous gamma globulin 1.0 g / (kg.d) with 2 d intravenous injection is a more effective and simple treatment.