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目的 :观察癫持续状态 (SE)所致急性肾功能的损害 ,寻找治疗及预防对策。方法 :34例患者急诊入院后 ,立即予地西泮、苯巴比妥等 ,并快速建立静脉通道 ,予甘露醇、呋塞米及碳酸氢钠、脑神经保护剂等 ,同时观测肾功能的变化。结果 :1 8例 (52 .94% )出现不同程度的肾功能损害 ;5例 (1 4 .71 % )出现急性肾功能衰竭 ,给予血液透析 1～ 2次 ;病死 2例 (5 .88% )。结论 :选择强有力、见效快、作用时间长、副作用小且首次足量的抗惊厥药 ,尽快控制SE是预防急性肾功能衰竭的关键。
Objective: To observe the damage of acute renal function induced by epileptic seizure (SE) and find the treatment and preventive measures. Methods: Thirty-four patients were admitted to the hospital immediately after diazepam, phenobarbital, etc., and quickly established intravenous access to mannitol, furosemide and sodium bicarbonate, neuroprotective agents, while observing renal function Variety. Results: 18 cases (52.94%) had varying degrees of renal dysfunction; 5 cases (14.71%) had acute renal failure, giving hemodialysis 1 ~ 2 times; 2 died of disease (5.88% ). CONCLUSIONS: Selective, potent, fast-acting, long-acting, less-toxic and first-sufficient anticonvulsant drugs may be the key to preventing acute renal failure as soon as possible.