青霉素对钩端螺旋体无论在体内体外皆有杀灭作用,用于钩端螺旋体病早期患者有特效。治疗时当注射青霉素后,由于被杀死的螺旋体释放出大量毒素和溶出成份对已致敏机体可发生过敏反应,常称青霉素治疗反应,旧称赫赛麦反应(Herxheimer Penicillin on Leptospira both in vivo and in vitro killing effect for the early detection of leptospirosis patients have special effects. Treatment when injection of penicillin, the spirochete is killed due to the release of a large number of toxins and dissolution of the sensitized body can have an allergic reaction, often referred to as penicillin treatment response, formerly known as the response to Hercynimer (Herxheimer