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目的 探讨促胃液素（Ｇａｓ） 、生长抑素（ＳＳＴ） 与胃肠道功能紊乱发生的关系．方法 用ＲＩＡ 方法检测胃肠道功能紊乱模型大鼠体液及组织中Ｇａｓ，ＳＳＴ 含量的变化，并用四君子汤反证．结果 与正常对照相比，胃肠道功能紊乱时血浆、胃液、肠液、胃窦、十二指肠、下丘脑组织中 Ｇａｓ 含量低下（ 分别为１０９－４６ ｎｇ／ Ｌ ±４０－８８ ｎｇ／ Ｌ， ３０－７８ ｎｇ／ Ｌ ±６－８１ ｎｇ／ Ｌ，９６－５８ ｎｇ／ Ｌ ±１４－３６ ｎｇ／ Ｌ， ２３２－６１ ｎｇ／ ｇ ±５３－８８ ｎｇ／ ｇ，２２－４７ ｎｇ／ ｇ ± ３－０２ ｎｇ／ ｇ ， ６８－０９ ｎｇ／ ｇ ± １３－４０ ｎｇ／ ｇ，Ｐ 均＜ ０－０５） ， ＳＳＴ 含量增高（ 分别为３２－５６ ｎｇ／ Ｌ ±７－９１ ｎｇ／ Ｌ， ２９－２１ ｎｇ／ Ｌ ± ４－５８ ｎｇ／ Ｌ， ２５－７４ ｎｇ／ Ｌ ±４－１６ ｎｇ／ Ｌ， ３６７－１５ ｎｇ／ ｇ ± ４２－３０ ｎｇ／ ｇ ， ４７－３１ ｎｇ／ ｇ ±１０－９７ ｎｇ／ ｇ ，６６－７６ ｎｇ／ ｇ ±６－５５ ｎｇ／ ｇ ， Ｐ 均＜ ０－０５） ． 经四君子汤预防和治疗的胃肠道功能紊乱模型大鼠，Ｇａｓ 和ＳＳＴ 水平均得到明显的改善，明显优于自然恢复大鼠（ Ｐ＜ ０－
Objective To investigate the relationship between gastrin, somatostatin (SST) and gastrointestinal disorders. Methods The contents of Gas and SST in body fluids and tissues of rats with gastrointestinal dysfunction were detected by RIA method and the syndrome of Sijunzi Decoction was used. Results Compared with the normal control group, Gas content in plasma, gastric juice, intestinal juice, gastric antrum, duodenum and hypothalamus was low in the patients with gastrointestinal disorders (109-46 ng / L ± 40-88 ng / L , 30-78 ng / L ± 6-81 ng / L, 96-58 ng / L ± 14-36 ng / L, 232-61 ng / g ± 53-88 ng / g, 22-47 ng / g ± 3-02 ng / g, 68-09 ng / g ± 13-40 ng / g, all P <0-05) and increased SST levels (32-56 ng / L ± 7-91 ng / L, 29 -21 ng / L ± 4-58 ng / L, 25-74 ng / L ± 4-16 ng / L, 367-15 ng / g ± 42-30 ng / g, 47-31 ng / g ± 10- 97 ng / g, 66-76 ng / g ± 6-55 ng / g P <0-05). Gastrointestinal dysfunction model rats treated by Sijunzi Decoction significantly improved the levels of Gas and SST, which were significantly better than that of spontaneously recovered rats (P <0-