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目的 比较布地奈德模特罗粉吸入与氨茶碱片口服治疗缓解期慢性阻塞性肺疾病(chronic obstructive pul?monary disease,COPD)的疗效及对患者血气指标、肺功能影响.方法 研究对象选取海南省第三人民医院2015年5月—2017年5月间收治的缓解期COPD患者146例,按照入院ID随机分为试验组与对照组,每组各73例.对照组患者予以氨茶碱片口服治疗,试验组患者予以布地奈德福莫特罗干粉吸入治疗.比较两组患者总有效率、肺功能、血气指标、生活质量、变化呼吸困难指数(transition dyspnoea index,TDI)及6min步行试验(6 minute walking test,6MWT).结果 治疗前,两组患者肺功能、血气指标、TDI、6MWT及生活质量均无显著差异(均P>0.05).治疗后,试验组患者总有效率显著高于对照组(P<0.05);两组患者肺功能、血气指标、TDI及6MWT水平较治疗前均显著改善(均P<0.05),且试验组患者肺功能、血气指标、TDI、6MWT及生活质量均显著优于对照组(均P0.05). After treatment, the total effective rate of the experimental group was 89.81%, significantly higher than that of the control group(73.15%, P<0.05), The FEV 1%)、forced vital capacity( FVC), inspiratory capacity(IC), pres?sure of arterial oxygen(PaO2), pressure of arterial carbon dioxide(PaCO2), PaCO2), and 6MWT levels were all signifi?cantly better than those of the control group(all P<0.05). Conclusion Budesonide fompdrol dry powder inhalation is more effective than aminophylline treated orally in treating COPD in remission stage, especially in blood gas indexes and lung function optimization.