论文部分内容阅读
目的研究典型与不典型下丘脑错构瘤的MRI表现及临床特点,从而进一步提高对该病的认识。资料与方法分析经临床及MRI共同诊断的10例下丘脑错构瘤的特征。结果典型MRI表现5例,T1WI上错构瘤均表现为均匀等信号团块,与脑皮质信号相似,T2WI上肿块呈稍高信号。肿瘤以广基底或带蒂与灰结节和乳头体相连,增强后肿瘤未见明显强化。不典型MRI表现5例,肿瘤体积较大,合并坏死囊变,肿瘤可位于鞍背区或视交叉上方,增强后肿瘤实质部分未见明显强化。结论当患儿出现性早熟和(或)痴笑样癫痫为主的临床表现时,MRI显示下丘脑附近区域结节或肿块时,无论是否为典型下丘脑错构瘤MRI表现,若增强后肿瘤实质部分未见明显强化时,均应首先考虑本病。
Objective To study the MRI features and clinical features of typical and atypical hypothalamic hamartoma, so as to further improve the understanding of the disease. Materials and Methods The characteristics of hypothalamic hamartoma in 10 cases diagnosed by clinical and MRI were analyzed. Results The typical MRI findings were all found in 5 cases. The hamartomas on T1WI showed homogeneous signal clumps. Similar to cortical signals, the tumors on T2WI showed a slightly higher signal. Tumor with a broad base or pedunculated with gray nodules and nipple body connected, enhanced tumor showed no significant enhancement. Atypical MRI findings in 5 cases, the tumor volume larger, with necrotic cystic lesions can be located in the dorsal raphe or the optic chiasm above the enhanced part of the tumor did not significantly enhanced. Conclusions When MRI showed the nodules or lumps in the vicinity of the hypothalamus in children with precocious puberty and / or craze-like epilepsy, whether MRI is typical of hypothalamic hamartoma or not, Some did not see significant strengthening, should first consider the disease.