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[目的]调查广州地区女性不同人群单纯疱疹病毒-2(HSV-2)感染情况及有关危险因素。[方法]由性病艾滋病高危人群干预工作队成员对流动人口、妇科门诊、性工作者等不同人群中的女性进行现场问卷调查,并采集血液标本,ELISA法检测HSV-2抗体、HIV,RPR/TPPA确诊梅毒,宫颈拭子检测沙眼衣原体,淋球菌等。[结果]调查对象HSV-2抗体总体阳性率为24.5%,流动人口、妇科门诊、性工作者女性HSV-2阳性率分别为14.6%、18.7%、47.5%;HSV-2感染独立危险因素包括有非固定性伴、初次性生活年龄小于20岁以及阴道异常分泌物、每周性生活频率多于3次;年龄26￣34岁为HSV-2感染的保护因素。[结论]广州地区女性人群中,性工作者HSV-2感染率最高,性工作者是性病行为干预的重点。多个性伴、性生活频率越高、初次性生活年龄越早越有可能感染HSV-2。
[Objective] To investigate the prevalence and risk factors of herpes simplex virus-2 (HSV-2) infection among different groups of women in Guangzhou. [Methods] The intervention group of high risk population of STD and AIDS patients conducted questionnaire survey on women in different population, such as floating population, gynecology clinic, sex worker and so on, and collected blood samples. ELISA, ELISA, TPPA confirmed syphilis, cervical swab Chlamydia trachomatis, Neisseria gonorrhoeae and so on. [Results] The overall positive rate of HSV-2 antibody in the surveyed subjects was 24.5%. The positive rates of HSV-2 in floating population, gynecology clinic and sex workers were 14.6%, 18.7% and 47.5% respectively. The independent risk factors of HSV-2 infection included Have non-fixed partner, the first sex life less than 20 years old and vaginal abnormal secretion, more than 3 times weekly sexual life; age 26 to 34 years of age as HSV-2 infection protective factors. [Conclusion] The prevalence of HSV-2 among sex workers in Guangzhou is the highest among sex workers, and sex workers are the focus of sexually transmitted diseases. Multiple sexual partners, the higher the frequency of sexual life, the younger the first sexual life more likely to be infected with HSV-2.