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目的:评价氨基糖苷类药物的安全性及合理性,以供临床医师合理用药参考,同时为规范临床用药提供依据。方法:抽取2011年9月1日到30日的门诊处方,共计5000张,同时抽取同年3月到12月出院病历300份,对其内容进行分析、比较和评价。结果:使用频率,门诊6.1%,住院12.0%。静脉注射50%。治疗有效的病例,内科有50.3%,外科有73.1%。出现副作用的有3.6%。结论:氨基糖苷类药物有着独特的化学性质和药理特点,是临床上抗感染治疗的重要药物,临床实践中要通过注意合理用药以尽可能避免药物的不当使用,使其发挥更大的作用。
OBJECTIVE: To evaluate the safety and rationality of aminoglycosides for the reference of rational use by clinicians, and to provide basis for regulating clinical medication. Methods: Outpatient prescriptions were collected from September 1, 2011 to September 30, a total of 5000, and at the same time, 300 medical records were collected from March to December in the same year, and their contents were analyzed, compared and evaluated. Results: The frequency of use, outpatient 6.1%, hospital 12.0%. Intravenous injection of 50%. Treatment of effective cases, the internal medicine was 50.3%, surgical 73.1%. There are 3.6% side effects. Conclusion: Aminoglycosides have unique chemical and pharmacological properties and are important drugs for anti-infective therapy in clinic. In clinical practice, they should play a more important role by avoiding rational use of drugs by paying attention to rational use of drugs.