以D-甘露糖为原料,分别利用苄胺双取代和aza-Wittig反应,再经氧化和亲核取代反应,合成了带保护基的含叠氮基及醛基的五元及六元氮杂糖中间体,对相关反应条件、基团保护及反应机理等进行了探讨,并提供了一种选择性脱除三苯甲基保护基的方法. Using D-mannose as raw materials, five-membered and six-membered azasugar containing azido groups and aldehyde groups with protecting groups were synthesized by benzylamine disubstituted and aza-Wittig reactions respectively. Intermediates, the related reaction conditions, group protection and reaction mechanism were discussed, and provided a selective removal of trityl protecting group method.