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使用硫酸锌治疗肝豆状核变性(以下简称HLD)的报道国内尚不多见1985年1月～7月,我们先后发现5例患者并用硫酸锌治疗,均获满意疗效。现报告如下。 例1 女,22岁 于1985年3月开始右上肢不自主震颤、无力,很快波及左上肢且进行性加重。2个月后震颤延及四肢,同时出现讲话不清、流涎、步态不稳,智力减退、精神呆滞等。患者9岁时曾患过肝炎。父母表情正常,非近亲婚配。一弟一妹均患同样疾病。检查:神清,表情淡漠,时有强笑面容。双眼角膜有K-F环。肝肋下不大,脾肋下可及,语言不清、四肢肌张力增高,四肢均见不自主震颤,震颤幅度大,腱反射及腹壁反射减弱,病理反射(-)。化验检查,红细胞310万/mm~3、
The use of zinc sulfate in the treatment of hepatolenticular degeneration (hereinafter referred to as HLD) reported in China is not yet seen in January 1985 to July, we have found five patients treated with zinc sulfate, were satisfactory results. The report is as follows. Example 1 Female, 22 years old Starting in March 1985, the right upper extremity involuntary tremors, weakness, quickly spread to the left upper extremity and progressive increase. Two months later tremor extended to the limbs, at the same time there is unclear speech, salivation, unsteady gait, mental retardation, mental retardation and so on. The patient had had hepatitis 9 years old. Parents normal expression, non-relatives marriage. One brother and one sister are suffering from the same disease. Check: God clear expression indifference, when a strong smile. Cornea with K-F ring. Liver under the ribs is not large, spleen and ribs accessible, the language is not clear, limb muscle tension increased, limb involuntary tremor, tremor amplitude, tendon reflex and abdominal wall reflex, pathological reflex (-). Laboratory tests, erythrocytes 3.1 million / mm ~ 3,