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蛋白Z是一种维生素K依赖性蛋白,作为蛋白Z依赖的蛋白酶抑制剂(ZPI)的辅因子,在磷脂和钙离子存在的条件下,能够抑制因子Xa,ZPI也能抑制因子Ⅺa。蛋白Z,ZPI与血栓性疾病中的关系已有初步研究。
Protein Z is a vitamin K-dependent protein that acts as a cofactor for the protein Z-dependent protease inhibitor (ZPI) and inhibits factor Xa in the presence of phospholipids and calcium ions, and inhibits factor XIa as well. The relationship between protein Z, ZPI and thrombotic diseases has been preliminary studied.