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5. Sustained release of isoniazid from polylactide microspheres prepared using solid/oil drug loading

Sustained release of isoniazid from polylactide microspheres prepared using solid/oil drug loading

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：songxin_gkong

【摘 要】

：

Polylactide(PLA) microspheres were prepared using the solid-in-oil(S/O) spray-drying method to achieve the sustained release of a hydrophilic drug for the treat

【作 者】

：

Limei Zhang Ying Li Yun Zhang 

【机 构】

：

InstituteofMedicinalPlantDevelopment

【出 处】

：

中国科学：生命科学英文版

【发表日期】

：

2016年7期

【关键词】

：

聚乳酸微球 肺结核 异烟肼 治疗 固体 缓释 制备 药物浓度 isoniazid  polylactide microspheres  sustained re 

【基金项目】

：

Acknowledgements This study was supported by the 12th Five-Year Important National Science ＆ Technology Specific Projects, and the National Science ＆ Technology Major Special Project on the Prevention

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Polylactide(PLA) microspheres were prepared using the solid-in-oil(S/O) spray-drying method to achieve the sustained release of a hydrophilic drug for the treatment of tuberculosis, via intratracheal instillation. Isoniazid(IN), a low-molecular-weight hyd

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