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目的比较宫颈病变的三种筛查方法--宫颈刮片脱落细胞、宫颈液基薄层细胞学(TCT)、阴道镜检查结合宫颈活组织病理检查的结果,评价三种筛查方法对诊断宫颈病变的价值。方法回顾性分析2008年1月至2010年12月门诊就诊的妇女,分别采用宫颈刮片、TCT、阴道镜检查结合宫颈活组织病理检查结果,对三种方法诊断宫颈疾病的结果进行比较。结果宫颈刮片5330例,结果异常145例,阳性检出率为2.72%;共有2016例进行TCT检查,结果异常者136例,阳性检出率为6.75%,共有2487例行阴道镜检查,发现异常图像696例,阳性检出率为27.99%。三种方法的阳性检出率比较差异有统计学意义(P<0.01),以阴道镜检查为最高,其次为TCT,最低是宫颈刮片。与组织病理结果比较,涂片的敏感性为39.31%,TCT的敏感性为48.53%,阴道镜的敏感性为22.84%,宫颈刮片与TCT差异无统计学意义(P>0.05),但阴道镜与TCT及宫颈刮片比较差异有统计学意义(P<0.01)。结论三种方法对宫颈病变都具有一定检出率,阴道镜检查可以提高诊断检出率,且简便、经济、及时,可以成为宫颈病变首选的筛查方法。
Objective To compare the results of three screening methods of cervical lesions - exfoliated cells of cervical smears, thin layer cytology of cervical fluid (TCT), colposcopy combined with biopsy of cervix and evaluation of three screening methods for diagnosis of cervical The value of the disease. Methods A retrospective analysis of women from outpatient clinics from January 2008 to December 2010 were performed with cervical smear, TCT, colposcopy and cervical biopsy. Results of the three methods in diagnosing cervical diseases were compared. Results There were 5330 cervical smears with 145 cases of abnormal results, the positive rate was 2.72%. A total of 2016 cases were diagnosed by TCT, 136 cases were abnormal. The positive rate was 6.75%. A total of 2487 colposcopy findings were found Abnormal images 696 cases, the positive detection rate was 27.99%. The positive rates of the three methods were statistically significant (P <0.01), colposcopy was the highest, followed by TCT, and the lowest was cervical smear. Compared with histopathological results, the sensitivity of smear was 39.31%, the sensitivity of TCT was 48.53%, the sensitivity of colposcopy was 22.84%. There was no significant difference between cervical smear and TCT (P> 0.05) Mirror and TCT and cervical smear difference was statistically significant (P <0.01). Conclusion All three methods have a certain detection rate of cervical lesions, colposcopy can improve the diagnostic detection rate, and simple, economical and timely, cervical lesions can become the preferred screening method.