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目的:观察前列地尔对急性脑梗死患者血液流变学的影响。方法:回顾性分析我院2007年6月-2010年2月治疗的86例急性脑梗死患者的临床资料。结果:治疗组的治疗效果显著优于对照组,且治疗组的低切黏度、红细胞压积、纤维蛋白原、最大血小板聚集率、红细胞聚集指数改变量下降幅度显著较大,与对照组比较差异具有统计学意义(P<0.05)。结论:前列地尔对改善急性脑梗死患者的血液流变学异常具有积极的作用,值得临床推广应用。
Objective: To observe the effect of alprostadil on hemorheology in patients with acute cerebral infarction. Methods: The clinical data of 86 patients with acute cerebral infarction treated in our hospital from June 2007 to February 2010 were retrospectively analyzed. Results: The therapeutic effect of the treatment group was significantly better than that of the control group. The changes of low-shear viscosity, hematocrit, fibrinogen, maximal platelet aggregation rate and erythrocyte aggregation index in the treatment group were significantly decreased compared with the control group Statistically significant (P <0.05). Conclusion: Alprostadil plays a positive role in the improvement of hemorrheology in patients with acute cerebral infarction, which is worthy of clinical application.