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目的探讨卵巢甲状腺肿类癌的临床病理特点和生物学行为.方法对3例卵巢甲状腺肿类癌进行临床病理分析及免疫组化染色观察.结果2例为混合型,1例为瘤壁结节型;组织学上2例以梁状结构为主,其中混有巢状结构,1例是梁状和小管状结构;免疫组化表型:3例syn和cgA均阳性;TG甲状腺滤泡区阳性,而类癌区阴性,同时做S-100均阴性,其中1例cgA弱阳性.结论卵巢甲状腺肿类癌是一种伴有甲状腺滤泡分化的低度恶性神经内分泌癌.
Objective To investigate the clinicopathological characteristics and biological behavior of ovarian goiter carcinomas.Methods Three cases of ovarian goiter carcinomas were observed by clinicopathological analysis and immunohistochemistry staining.Results Two cases were mixed and one case was tumor wall nodules Type; histological 2 cases of beam-shaped structure, which mixed with nested structure, 1 case of beam-shaped and small tubular structure; immunohistochemical phenotype: 3 cases of syn and cgA were positive; TG thyroid follicular area Positive, while the carcinoid area negative, while S-100 were negative, of which 1 case of weak positive cgA.Conclusion Ovarian goiter carcinoid is a thyroid follicular differentiation associated with low-grade neuroendocrine carcinoma.