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妊娠和癌症在用羊水及血浆所观察到的白细胞移动增强(LME)现象有力地证明了二者在反应性方面有对抗原不排斥的共同机理,不仅在体外实验,人体内可能也如此,只有妊娠和癌的抗原组织不被免疫适应宿主所排斥。此免疫耐受性显然对妊娠有利却给癌症患者带来灾难性的后果。近来妊娠免疫研究的进展提出妊娠不受排斥的类似机理早就在许多肿瘤系统中描述过。在肿瘤系统中已确定的三种最重要的机理:封闭抗体(IgG),免疫复合物(抗原抗体),及抑制T-细胞等最近已在妊娠
Pregnancy and Cancer The phenomenon of enhanced leukocyte migration (LME) observed with amniotic fluid and plasma has strongly demonstrated that both have a common mechanism of reactivity with respect to non-exclusion of antigens, not only in in vitro experiments, but also in humans Antigen tissues of pregnancy and cancer are not rejected by the immune adaptation host. This immune tolerance is clearly beneficial to pregnancy, but has devastating consequences for cancer patients. Recent Developments in Pregnancy Immunization Studies A similar mechanism of non-rejection of pregnancy has long been described in many oncology systems. Three of the most important mechanisms identified in the tumor system: blocking antibodies (IgGs), immune complexes (antigenic antibodies), and the inhibition of T-cells have recently been identified in pregnancy