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目的:探讨乌司他丁联合甲泼尼龙治疗重症急性胰腺炎的临床疗效。方法:将48例重症急性胰腺炎患者随机分为观察组25例和对照组23例,治疗组使用乌司他丁联合甲泼尼龙进行治疗,对照组仅使用甲泼尼龙,其余治疗措施及方法基本相同;对比临床疗效、并发症发生率、血液淀粉酶恢复正常的时间及患者住院时间。结果:治疗组症状和体征消失时间低于对照组,差异有统计学意义(p<0.05),并发症发生率和住院时间也明显低于对照组(p<0.05)。结论:乌司他丁与甲泼尼龙联合能明显改善重症急性胰腺炎患者的体征,缩短住院时间,疗效好,值得推广。
Objective: To investigate the clinical efficacy of ulinastatin combined with methylprednisolone in the treatment of severe acute pancreatitis. Methods: Forty-eight patients with severe acute pancreatitis were randomly divided into observation group (n = 25) and control group (n = 23). The treatment group was treated with ulinastatin combined with methylprednisolone and the control group only with methylprednisolone. The remaining treatment measures and methods Basically the same; compare the clinical efficacy, the incidence of complications, blood amylase return to normal time and patient hospital stay. Results: The disappearance time of symptoms and signs in the treatment group was lower than that in the control group (p <0.05). The incidence of complications and hospital stay were also significantly lower than those in the control group (p <0.05). Conclusion: The combination of ulinastatin and methylprednisolone can significantly improve the signs of patients with severe acute pancreatitis, shorten the hospital stay, good curative effect and worthy of promotion.