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目的了解亚低温治疗对心肺复苏后患者肺功能的影响。方法选取2012年1月-2014年12月医院心肺复苏成功病例32例,随机分为亚低温组与常温组各16例。2组均予常规治疗处理,在此基础上亚低温组予亚低温治疗,常温组予冰帽局部降温治疗。比较2组患者的血气分析和肺顺应性情况。结果亚低温组PO2、PCO2水平优于常温组,比较差异有统计学意义(P<0.05)。治疗后亚低温组动态顺应性升高,气道峰压降低,与治疗前比较差异有统计学意义(P<0.05),2组治疗后动态顺应性、气道峰压比较差异有统计学意义(P<0.05)。余项比较差异无统计学意义(P>0.05),提示亚低温组患者肺功能改善。结论亚低温治疗能抑制肺部的缺血再灌注损伤,对肺起保护作用。
Objective To investigate the effect of mild hypothermia on pulmonary function in patients after cardiopulmonary resuscitation. Methods From January 2012 to December 2014, 32 cases of successful cardiopulmonary resuscitation were randomly divided into mild hypothermia group and normal temperature group of 16 cases. The two groups were given conventional treatment, on the basis of mild hypothermia to mild hypothermia treatment, ice cap cooling at room temperature group. Blood gas analysis and lung compliance were compared between the two groups. Results The levels of PO2 and PCO2 in the hypothermia group were better than those in the normal temperature group (P <0.05). After treatment, the dynamic compliance of the mild hypothermia group was increased and the peak airway pressure was decreased, which was significantly different from that before treatment (P <0.05). There was significant difference between the two groups in dynamic compliance and peak airway pressure (P <0.05). There was no significant difference in the remaining items (P> 0.05), suggesting that patients with mild hypothermia improved pulmonary function. Conclusion Mild hypothermia can inhibit lung ischemia-reperfusion injury and protect the lungs.