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Bcl-2蛋白家族在细胞编程死亡的调控中起重要的作用。本文综述了Bcl-2家族新成员Bak的特点及其生物学活性,并就Bak及Bcl-2家族成员对细胞死亡调控机制进行了初步探讨。
The Bcl-2 protein family plays an important role in the regulation of programmed cell death. This review summarizes the characteristics and biological activities of Bak, a new member of the Bcl-2 family, and explores the mechanisms by which Bak and Bcl-2 family members regulate cell death.