早产儿应激性溃疡出血是全身应激反应的临床表现之一,以上消化道出血为主要临床表现,是早产儿重症疾病的并发症,死亡率较高,及时的明确诊断,积极治疗原发病,采取综合有效的治疗,可以降低死亡率,改善预后。1资料与方法 1.1临床资料2004年1月~2013年1月我院新生儿科共收治重症疾病早产儿316例,男性170例,女性146例;新生儿重度窒息20例,颅内出血50例,低出生体质量儿50例,新生儿败血症50例,胎粪吸入综合征40例,缺氧缺血性脑损伤36例,寒冷损伤综合征14例,感染 Stress ulcer bleeding in premature infants is one of the clinical manifestations of systemic stress response, the above gastrointestinal bleeding as the main clinical manifestations of complications of premature infants with severe diseases, higher mortality, timely and clear diagnosis of active treatment of primary Disease, to take comprehensive and effective treatment, can reduce mortality and improve prognosis. 1 Materials and Methods 1.1 Clinical data January 2004 ~ January 2013 in our hospital were admitted to the Department of Neonatology, 316 cases of preterm infants with severe diseases, 170 males and 146 females; neonatal severe asphyxia in 20 cases, 50 cases of intracranial hemorrhage, low Birth weight of 50 children, neonatal sepsis in 50 cases, meconium aspiration syndrome in 40 cases, hypoxic-ischemic brain damage in 36 cases, 14 cases of cold injury syndrome, infection