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单克隆抗体对干扰素的特异性很高,本文报道用单克隆抗体鉴别有活性与无活性的干扰素的研究结果。实验采用重组人白细胞干扰素A(IFLγA)和抗人白细胞干扰素单克隆抗体LI-1～LI-12。抗病毒活性测定采用细胞病变抑制法。干扰素的放射免疫测定(RIA)采用双抗
Monoclonal antibodies are highly specific to interferon. We report here the results of the identification of active and inactive interferons using monoclonal antibodies. The experiment used recombinant human leukocyte interferon A (IFLγA) and anti-human leukocyte interferon monoclonal antibody LI-1 ~ LI-12. Antiviral activity assay using cytopathic inhibition. Interferon radioimmunoassay (RIA) using double anti