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目的:考察自制的四味紫草烧伤膏和八味紫草烧伤膏对烧伤后创面修复和镇痛的影响。方法:以大鼠Ⅱ度烫伤模型和小鼠热板法,分别观察两种烧伤膏对创面的促进愈合作用和镇痛作用。结果:四味紫草烧伤膏1.0g/只剂量组可以减轻烧伤创面早期加深,缩短大鼠Ⅱ度烧伤创面愈合时间,提高愈合率,改善创面皮肤状态,且具有快速镇痛的特点,而八味紫草烧伤膏1.0g/只剂量组不能改善烧伤创面的皮肤组织。结论:四味紫草烧伤膏具有促进创面愈合和镇痛作用。
OBJECTIVE: To investigate the effects of self-made Siwei Zhuruji Ointment and Baweizhi Burn Ointment on wound healing and analgesia after burn injury. Methods: The model of Ⅱ degree scald in rats and the hot plate method in mice were used to observe the promoting healing and analgesic effects of the two kinds of burn ointment on wounds. Results: The dosage of 1.0g / dose of Simvastatin Burn Ointment could reduce the early deepening of burn wounds, shorten the healing time of second degree burn wounds in rats, improve the healing rate, improve the skin condition of wounds and have the characteristics of rapid analgesia. Flammulina burn cream 1.0g / only dose group can not improve the burn wound skin tissue. Conclusion: Siwei Zhisao Burn Ointment can promote wound healing and analgesia.