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目的:探讨动脉化疗栓塞治疗联合三维适形放疗在原发性肝癌患者中的应用及效果。方法:选取辽宁省肿瘤医院肿瘤科2010年1月至2012年12月收治的70例原发性肝癌患者作为研究对象,应用随机数字表法将患者分为对照组和实验组,每组患者各35例,比较两组患者临床疗效、甲胎蛋白(AFP)水平变化和药物毒副反应发生情况。结果:实验组患者AFP明显低于对照组患者的,差异有显著性(P<0.05),实验组患者肿瘤大小明显小于对照组患者的,差异有显著性(P<0.05),实验组患者治疗总有效率(91.43%)明显高于对照组患者治疗总有效率为(65.71%),差异有显著性(P<0.05),与对照组患者相比,试验组患者药物毒副反应发生率未见明显增加,差异无显著性(P>0.05)。结论:肝动脉化疗栓塞联合三维适形放疗综合治疗原发性肝癌临床疗效确切,优于肝动脉化疗栓塞,具有安全高效和不良反应少等特点。
Objective: To investigate the application of arterial chemoembolization combined with three-dimensional conformal radiotherapy in patients with primary liver cancer. Methods: Seventy patients with primary liver cancer who were admitted to Department of Oncology, Liaoning Cancer Hospital from January 2010 to December 2012 were selected as research objects. Patients were divided into control group and experimental group by random number table method. 35 cases. The clinical efficacy, the level of AFP and the side effects of drugs were compared between the two groups. Results: The AFP in the experimental group was significantly lower than that in the control group (P <0.05). The tumor size in the experimental group was significantly smaller than that in the control group (P <0.05) The total effective rate (91.43%) was significantly higher than that of the control group (65.71%), the difference was significant (P <0.05). Compared with the control group, the incidence of drug toxicity See significantly increased, the difference was not significant (P> 0.05). Conclusion: Hepatic arterial chemoembolization combined with three-dimensional conformal radiotherapy comprehensive treatment of primary liver cancer clinical curative effect is better than hepatic arterial chemoembolization, with safe and efficient and less adverse reactions and so on.