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目的观察肺癌与血栓栓塞性疾病的关系,探讨其发病机理及治疗方法。方法对经病理及临床证实的14例肺癌合并血栓栓塞性疾病进行分析。结果病理组织学证实为12例腺癌患者,血D—二聚体明显升高,血小板数增加,合并肺栓塞时肺动脉压升高,合并脑梗塞脑CT可确诊。结论50岁以上的人出现不能解释的血栓及少见类型的血栓栓塞性疾病应考虑有肿瘤的可能,肺癌合并血栓栓塞的患者死亡率明显增加。抗凝和溶栓是治疗本病的主要方法。
Objective To observe the relationship between lung cancer and thromboembolic diseases, and to explore its pathogenesis and treatment methods. Methods 14 cases of lung cancer with thromboembolic disease confirmed by pathology and clinical analysis were analyzed. RESULTS: Histopathologically confirmed 12 patients with adenocarcinoma, the blood D-dimer was significantly elevated, the platelet count was increased, the pulmonary arterial pressure was increased with pulmonary embolism, and cerebral CT with cerebral infarction could be confirmed. Conclusion Unexplained thrombosis and uncommon types of thromboembolic disease in patients over 50 years of age should consider the possibility of tumor, and the mortality of patients with lung cancer and thromboembolism is significantly increased. Anticoagulation and thrombolysis are the main methods of treating this disease.